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TitleTargeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy.
Journal, issue, pagesSci Adv, Vol. 10, Page eadg7887-eadg7887, Year 2024
Publish dateNov 30, 2022 (structure data deposition date)
AuthorsStanford, S.M. / Nguyen, T.P. / Chang, J. / Zhao, Z. / Hackman, G.L. / Santelli, E. / Sanders, C.M. / Katiki, M. / Dondossola, E. / Brauer, B.L. ...Stanford, S.M. / Nguyen, T.P. / Chang, J. / Zhao, Z. / Hackman, G.L. / Santelli, E. / Sanders, C.M. / Katiki, M. / Dondossola, E. / Brauer, B.L. / Diaz, M.A. / Zhan, Y. / Ramsey, S.H. / Watson, P.A. / Sankaran, B. / Paindelli, C. / Parietti, V. / Mikos, A.G. / Lodi, A. / Bagrodia, A. / Elliott, A. / McKay, R.R. / Murali, R. / Tiziani, S. / Kettenbach, A.N. / Bottini, N.
External linksSci Adv / PubMed:38295166
MethodsX-ray diffraction
Resolution1.59 Å
Structure data

PDB-8fbz:
Crystal Structure of apo human Glutathione Synthetase Y270E
Method: X-RAY DIFFRACTION / Resolution: 1.59 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsBIOSYNTHETIC PROTEIN / Glutathione Synthesis ATPase

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