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Title | PYK-SubstitutionOME: an integrated database containing allosteric coupling, ligand affinity and mutational, structural, pathological, bioinformatic and computational information about pyruvate kinase isozymes. |
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Journal, issue, pages | Database (Oxford), Vol. 2023, Year 2023 |
Publish date | Nov 15, 2022 (structure data deposition date) |
Authors | Swint-Kruse, L. / Dougherty, L.L. / Page, B. / Wu, T. / O'Neil, P.T. / Prasannan, C.B. / Timmons, C. / Tang, Q. / Parente, D.J. / Sreenivasan, S. ...Swint-Kruse, L. / Dougherty, L.L. / Page, B. / Wu, T. / O'Neil, P.T. / Prasannan, C.B. / Timmons, C. / Tang, Q. / Parente, D.J. / Sreenivasan, S. / Holyoak, T. / Fenton, A.W. |
External links | Database (Oxford) / PubMed:37171062 |
Methods | X-ray diffraction |
Resolution | 2.15 - 2.41 Å |
Structure data | PDB-8f5t: PDB-8f5u: PDB-8f6m: |
Chemicals | ChemComp-MG: ChemComp-NA: ChemComp-TRS: ChemComp-GOL: ChemComp-HOH: ChemComp-EDO: ChemComp-K: ChemComp-PYR: ChemComp-ADP: ChemComp-SIN: ChemComp-MN: ChemComp-ALA: ChemComp-GZ3: |
Source |
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Keywords | CYTOSOLIC PROTEIN / glycolysis / metabolic kinase / central metabolism |