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-Structure paper
Title | Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site. |
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Journal, issue, pages | Sci Rep, Vol. 12, Page 14561-14561, Year 2022 |
Publish date | Aug 4, 2022 (structure data deposition date) |
Authors | Goedken, E.R. / Argiriadi, M.A. / Dietrich, J.D. / Petros, A.M. / Krishnan, N. / Panchal, S.C. / Qiu, W. / Wu, H. / Zhu, H. / Adams, A.M. ...Goedken, E.R. / Argiriadi, M.A. / Dietrich, J.D. / Petros, A.M. / Krishnan, N. / Panchal, S.C. / Qiu, W. / Wu, H. / Zhu, H. / Adams, A.M. / Bodelle, P.M. / Goguen, L. / Richardson, P.L. / Slivka, P.F. / Srikumaran, M. / Upadhyay, A.K. / Wu, B. / Judge, R.A. / Vasudevan, A. / Gopalakrishnan, S.M. / Cox, P.B. / Stoll, V.S. / Sun, C. |
External links | Sci Rep / PubMed:36028520 |
Methods | X-ray diffraction |
Resolution | 1.49 - 2.28 Å |
Structure data | PDB-8dyf: PDB-8dyg: PDB-8dyh: PDB-8dyi: |
Chemicals | ChemComp-U5I: ChemComp-HOH: ChemComp-U5Q: ChemComp-U5X: ChemComp-GOL: ChemComp-U6C: |
Source |
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Keywords | CYTOKINE / dimer / fragment / inhibitor / antagonist |