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Title | A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations. |
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Journal, issue, pages | Plos Pathog., Vol. 19, Page e1011592-e1011592, Year 2023 |
Publish date | Jun 18, 2022 (structure data deposition date) |
Authors | Ou, J. / Lewandowski, E.M. / Hu, Y. / Lipinski, A.A. / Aljasser, A. / Colon-Ascanio, M. / Morgan, R.T. / Jacobs, L.M.C. / Zhang, X. / Bikowitz, M.J. ...Ou, J. / Lewandowski, E.M. / Hu, Y. / Lipinski, A.A. / Aljasser, A. / Colon-Ascanio, M. / Morgan, R.T. / Jacobs, L.M.C. / Zhang, X. / Bikowitz, M.J. / Langlais, P.R. / Tan, H. / Wang, J. / Chen, Y. / Choy, J.S. |
External links | Plos Pathog. / PubMed:37651467 |
Methods | X-ray diffraction |
Resolution | 2.78 - 2.8 Å |
Structure data | PDB-8ddi: PDB-8ddm: |
Chemicals | ChemComp-HOH: ChemComp-K36: |
Source |
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Keywords | VIRAL PROTEIN / Protease / SARS-CoV-2 / Mpro / Mutation |