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-Structure paper
Title | Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase. |
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Journal, issue, pages | J. Mol. Biol., Vol. 436, Page 168449-168449, Year 2024 |
Publish date | Feb 6, 2023 (structure data deposition date) |
Authors | Mpakali, A. / Barla, I. / Lu, L. / Ramesh, K.M. / Thomaidis, N. / Stern, L.J. / Giastas, P. / Stratikos, E. |
External links | J. Mol. Biol. / PubMed:38244767 |
Methods | X-ray diffraction |
Resolution | 2.62 - 3.03 Å |
Structure data | PDB-8cgp: PDB-8cgw: |
Chemicals | ChemComp-NAG: ChemComp-MLT: ChemComp-ZN: ChemComp-UKG: ChemComp-PEG: ChemComp-EDO: ChemComp-HOH: ChemComp-UJX: ChemComp-GLY: |
Source |
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Keywords | HYDROLASE / insulin-regulated aminopeptidase / allosteric inhibitor / aryl sulfonamides / antigen presentation / benzopyran scaffold / HFI-419 |