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Structure paper

TitleZNF524 directly interacts with telomeric DNA and supports telomere integrity.
Journal, issue, pagesNat Commun, Vol. 14, Page 8252-8252, Year 2023
Publish dateAug 12, 2022 (structure data deposition date)
AuthorsBraun, H. / Xu, Z. / Chang, F. / Viceconte, N. / Rane, G. / Levin, M. / Lototska, L. / Roth, F. / Hillairet, A. / Fradera-Sola, A. ...Braun, H. / Xu, Z. / Chang, F. / Viceconte, N. / Rane, G. / Levin, M. / Lototska, L. / Roth, F. / Hillairet, A. / Fradera-Sola, A. / Khanchandani, V. / Sin, Z.W. / Yong, W.K. / Dreesen, O. / Yang, Y. / Shi, Y. / Li, F. / Butter, F. / Kappei, D.
External linksNat Commun / PubMed:38086788
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-7ysf:
Crystal structure of ZNF524 ZF1-4 in complex with telomeric DNA
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-MLT:
D-MALATE

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/DNA / C2H2 zinc finger / DNA BINDING PROTEIN / TRANSFERASE-DNA complex

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