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Structure paper

TitleA growth selection system for the directed evolution of amine-forming or converting enzymes.
Journal, issue, pagesNat Commun, Vol. 13, Page 7458-7458, Year 2022
Publish dateApr 3, 2022 (structure data deposition date)
AuthorsWu, S. / Xiang, C. / Zhou, Y. / Khan, M.S.H. / Liu, W. / Feiler, C.G. / Wei, R. / Weber, G. / Hohne, M. / Bornscheuer, U.T.
External linksNat Commun / PubMed:36460668
MethodsX-ray diffraction
Resolution1.32 - 1.76 Å
Structure data

PDB-7xg5:
Crystal structure of an (R)-selective omega-transaminase mutant from Aspergillus terreus with PLP
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

PDB-7xg6:
Crystal structure of an (R)-selective omega-transaminase mutant from Aspergillus terreus with covalently bound PLP
Method: X-RAY DIFFRACTION / Resolution: 1.32 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-HOH:
WATER

Source
  • aspergillus terreus (strain nih 2624 / fgsc a1156) (mold)
KeywordsTRANSFERASE / alpha/beta dehydrogenase / LLP

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