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-Structure paper
Title | N -Aromatic-Substituted Indazole Derivatives as Brain-Penetrant and Orally Bioavailable JNK3 Inhibitors. |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 12, Page 1546-1552, Year 2021 |
Publish date | Sep 2, 2021 (structure data deposition date) |
Authors | Feng, Y. / Park, H. / Ryu, J.C. / Yoon, S.O. |
External links | Acs Med. Chem. Lett. / PubMed:34676036 |
Methods | X-ray diffraction |
Resolution | 2.11 Å |
Structure data | PDB-7s1n: |
Chemicals | ChemComp-86C: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/Inhibitor / MAPK10 / JNK3 / Kinase Inhibitor / Alzheimers Diseases / Indazole / Azaindazole / Neurodegeneration / TRANSFERASE / TRANSFERASE-Inhibitor complex |