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-Structure paper
Title | Relaxed Substrate Requirements of Sterol 14 alpha-Demethylase from Naegleria fowleri Are Accompanied by Resistance to Inhibition. |
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Journal, issue, pages | J. Med. Chem., Vol. 64, Page 17511-17522, Year 2021 |
Publish date | Aug 13, 2021 (structure data deposition date) |
![]() | Hargrove, T.Y. / Wawrzak, Z. / Rachakonda, G. / Nes, W.D. / Villalta, F. / Guengerich, F.P. / Lepesheva, G.I. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.11 Å |
Structure data | ![]() PDB-7rtq: |
Chemicals | ![]() ChemComp-HEM: ![]() ChemComp-7PW: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / CYTOCHROME P450 / CYP51 / sterol 14 alpha- demethylase |