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-Structure paper
Title | New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography. |
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Journal, issue, pages | J. Biol. Chem., Vol. 298, Page 101535-101535, Year 2022 |
Publish date | Jul 13, 2021 (structure data deposition date) |
![]() | Milano, S.K. / Huang, Q. / Nguyen, T.T. / Ramachandran, S. / Finke, A. / Kriksunov, I. / Schuller, D.J. / Szebenyi, D.M. / Arenholz, E. / McDermott, L.A. ...Milano, S.K. / Huang, Q. / Nguyen, T.T. / Ramachandran, S. / Finke, A. / Kriksunov, I. / Schuller, D.J. / Szebenyi, D.M. / Arenholz, E. / McDermott, L.A. / Sukumar, N. / Cerione, R.A. / Katt, W.P. |
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Methods | X-ray diffraction |
Resolution | 2.8 - 3 Å |
Structure data | ![]() PDB-7ren: ![]() PDB-7rgg: |
Chemicals | ![]() ChemComp-B4A: ![]() ChemComp-HOH: ![]() ChemComp-04A: |
Source |
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![]() | HYDROLASE/INHIBITOR / HYDROLASE-INHIBITOR complex / Inhibitor / Complex |