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Title | Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody. |
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Journal, issue, pages | Jacs Au, Vol. 3, Page 204-215, Year 2023 |
Publish date | Jan 17, 2022 (structure data deposition date) |
Authors | Lenza, M.P. / Atxabal, U. / Nycholat, C. / Oyenarte, I. / Franconetti, A. / Quintana, J.I. / Delgado, S. / Nunez-Franco, R. / Garnica Marroquin, C.T. / Coelho, H. ...Lenza, M.P. / Atxabal, U. / Nycholat, C. / Oyenarte, I. / Franconetti, A. / Quintana, J.I. / Delgado, S. / Nunez-Franco, R. / Garnica Marroquin, C.T. / Coelho, H. / Unione, L. / Jimenez-Oses, G. / Marcelo, F. / Schubert, M. / Paulson, J.C. / Jimenez-Barbero, J. / Ereno-Orbea, J. |
External links | Jacs Au / PubMed:36711084 |
Methods | X-ray diffraction |
Resolution | 2.34 - 3.352 Å |
Structure data | PDB-7qu6: PDB-7quh: PDB-7qui: |
Chemicals | ChemComp-HOH: ChemComp-F9I: |
Source |
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Keywords | IMMUNE SYSTEM / Siglec / sialic acid / antibody |