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Structure paper

TitleSpinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
Journal, issue, pagesJ. Biol. Chem., Vol. 298, Page 101903-101903, Year 2022
Publish dateOct 4, 2021 (structure data deposition date)
AuthorsCross, A.R. / Roy, S. / Vivoli Vega, M. / Rejzek, M. / Nepogodiev, S.A. / Cliff, M. / Salmon, D. / Isupov, M.N. / Field, R.A. / Prior, J.L. / Harmer, N.J.
External linksJ. Biol. Chem. / PubMed:35398092
MethodsX-ray diffraction
Resolution1.326 - 1.9 Å
Structure data

PDB-7pvi:
dTDP-sugar epimerase
Method: X-RAY DIFFRACTION / Resolution: 1.434 Å

PDB-7pwb:
dTDP-sugar epimerase from Coxiella burnetii in complex with dTDP
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-7pwh:
Structure of the dTDP-sugar epimerase StrM
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-7pwi:
Structure of the dTDP-sugar epimerase StrM
Method: X-RAY DIFFRACTION / Resolution: 1.326 Å

Chemicals

ChemComp-XYP:
beta-D-xylopyranose

ChemComp-XYS:
alpha-D-xylopyranose

ChemComp-NA:
Unknown entry

ChemComp-FLC:
CITRATE ANION

ChemComp-HOH:
WATER

ChemComp-TYD:
THYMIDINE-5'-DIPHOSPHATE

ChemComp-CIT:
CITRIC ACID

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-CA:
Unknown entry

Source
  • coxiella burnetii (strain rsa 493 / nine mile phase i) (bacteria)
  • streptomyces griseus (bacteria)
KeywordsSUGAR BINDING PROTEIN / Coxiella burnetii / O-antigen / epimerase / enzyme kinetics

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