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Title | P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate. |
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Journal, issue, pages | Acta Pharm Sin B, Vol. 13, Page 3561-3574, Year 2023 |
Publish date | Jun 2, 2021 (structure data deposition date) |
Authors | Zhang, S. / Zhang, L. / Greule, A. / Tailhades, J. / Marschall, E. / Prasongpholchai, P. / Leng, D.J. / Zhang, J. / Zhu, J. / Kaczmarski, J.A. ...Zhang, S. / Zhang, L. / Greule, A. / Tailhades, J. / Marschall, E. / Prasongpholchai, P. / Leng, D.J. / Zhang, J. / Zhu, J. / Kaczmarski, J.A. / Schittenhelm, R.B. / Einsle, O. / Jackson, C.J. / Alberti, F. / Bechthold, A. / Zhang, Y. / Tosin, M. / Si, T. / Cryle, M.J. |
External links | Acta Pharm Sin B / PubMed:37655329 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-7oq6: |
Chemicals | ChemComp-HEM: ChemComp-SCN: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / cytochrome P450 monooxygenase |