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-Structure paper
Title | Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38 alpha , and B-Raf. |
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Journal, issue, pages | J. Med. Chem., Vol. 64, Page 15651-15670, Year 2021 |
Publish date | Apr 12, 2021 (structure data deposition date) |
![]() | Patterson, J.R. / Graves, A.P. / Stoy, P. / Cheung, M. / Desai, T.A. / Fries, H. / Gatto Jr., G.J. / Holt, D.A. / Shewchuk, L. / Totoritis, R. ...Patterson, J.R. / Graves, A.P. / Stoy, P. / Cheung, M. / Desai, T.A. / Fries, H. / Gatto Jr., G.J. / Holt, D.A. / Shewchuk, L. / Totoritis, R. / Wang, L. / Kallander, L.S. |
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Methods | X-ray diffraction |
Resolution | 2.95 - 3.1 Å |
Structure data | ![]() PDB-7mgj: ![]() PDB-7mgk: |
Chemicals | ![]() ChemComp-ZFS: ![]() ChemComp-HOH: ![]() ChemComp-ZGD: |
Source |
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![]() | TRANSFERASE/INHIBITOR / kinase / CARK / TRANSFERASE / TRANSFERASE-INHIBITOR complex |