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TitleUnraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 143, Page 18467-18480, Year 2021
Publish dateJan 6, 2021 (structure data deposition date)
AuthorsWang, J. / Buchman, C.D. / Seetharaman, J. / Miller, D.J. / Huber, A.D. / Wu, J. / Chai, S.C. / Garcia-Maldonado, E. / Wright, W.C. / Chenge, J. / Chen, T.
External linksJ. Am. Chem. Soc. / PubMed:34648292
MethodsX-ray diffraction
Resolution2.65 Å
Structure data

PDB-7lad:
Clobetasol propionate bound to CYP3A5
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-XRD:
Clobetasol propionate

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / Cytochrome P450 / CYP3A5

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