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-Structure paper
Title | Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A. |
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Journal, issue, pages | Eur. J. Med. Chem., Vol. 227, Page 113948-113948, Year 2022 |
Publish date | Jul 30, 2021 (structure data deposition date) |
Authors | Miyazaki, Y. / Kikuchi, M. / Umezawa, K. / Descamps, A. / Nakamura, D. / Furuie, G. / Sumida, T. / Saito, K. / Kimura, N. / Niwa, T. ...Miyazaki, Y. / Kikuchi, M. / Umezawa, K. / Descamps, A. / Nakamura, D. / Furuie, G. / Sumida, T. / Saito, K. / Kimura, N. / Niwa, T. / Sumida, Y. / Umehara, T. / Hosoya, T. / Kii, I. |
External links | Eur. J. Med. Chem. / PubMed:34742017 |
Methods | X-ray diffraction |
Resolution | 2.42 - 2.68 Å |
Structure data | PDB-7fhs: PDB-7fht: |
Chemicals | ChemComp-4VZ: ChemComp-GOL: ChemComp-HOH: ChemComp-4WD: |
Source |
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Keywords | TRANSFERASE / DYRK1A / Kinase / Inhibitor |