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-Structure paper
Title | Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability. |
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Journal, issue, pages | Protein Eng. Des. Sel., Vol. 34, Year 2021 |
Publish date | Oct 13, 2020 (structure data deposition date) |
![]() | Maddi, E.R. / Raghavan, S.C. / Natesh, R. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.76 - 2.9 Å |
Structure data | ![]() PDB-7d9k: ![]() PDB-7d9y: |
Chemicals | ![]() ChemComp-HOH: |
Source |
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![]() | LIGASE / DBD / Native / ATP dependant ligase. / DBD mutant A3V / ATP dependant ligase / hypomorphic mutant |