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-Structure paper
Title | BET bromodomain inhibitors regulate keratinocyte plasticity. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 17, Page 280-290, Year 2021 |
Publish date | Jun 11, 2020 (structure data deposition date) |
Authors | Schutzius, G. / Kolter, C. / Bergling, S. / Tortelli, F. / Fuchs, F. / Renner, S. / Guagnano, V. / Cotesta, S. / Rueeger, H. / Faller, M. ...Schutzius, G. / Kolter, C. / Bergling, S. / Tortelli, F. / Fuchs, F. / Renner, S. / Guagnano, V. / Cotesta, S. / Rueeger, H. / Faller, M. / Bouchez, L. / Salathe, A. / Nigsch, F. / Richards, S.M. / Louis, M. / Gruber, V. / Aebi, A. / Turner, J. / Grandjean, F. / Li, J. / Dimitri, C. / Thomas, J.R. / Schirle, M. / Blank, J. / Drueckes, P. / Vaupel, A. / Tiedt, R. / Manley, P.W. / Klopp, J. / Hemmig, R. / Zink, F. / Leroy, N. / Carbone, W. / Roma, G. / Keller, C.G. / Dales, N. / Beyerbach, A. / Zimmerlin, A. / Bonenfant, D. / Terranova, R. / Berwick, A. / Sahambi, S. / Reynolds, A. / Jennings, L.L. / Ruffner, H. / Tarsa, P. / Bouwmeester, T. / Driver, V. / Frederiksen, M. / Lohmann, F. / Kirkland, S. |
External links | Nat. Chem. Biol. / PubMed:33462494 |
Methods | X-ray diffraction |
Resolution | 1.976 Å |
Structure data | PDB-6zci: |
Chemicals | ChemComp-QFN: ChemComp-HOH: |
Source |
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Keywords | TRANSCRIPTION / chromatin binding / bromodomain / acetylated histone binding / transcription regulation |