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TitleCrystal structure of Aurora A (STK6) in complex with macrocycle ODS2003208
Journal, issue, pagesTo Be Published
Publish dateMay 26, 2020 (structure data deposition date)
AuthorsChaikuad, A. / Benderitter, P. / Hoflack, J. / Denis, A. / Knapp, S. / Structural Genomics Consortium (SGC)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-6z4y:
Crystal structure of Aurora A (STK6) in complex with macrocycle ODS2003208
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-Q7Q:
6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / kinase / kinase inhibitor / aurora a / stk6 / macrocycle / nanocyclic / Structural Genomics / Structural Genomics Consortium / SGC

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