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-Structure paper
Title | Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. |
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Journal, issue, pages | Cell Chem Biol, Vol. 27, Page 1441-1451.e7, Year 2020 |
Publish date | Jan 26, 2020 (structure data deposition date) |
Authors | Maculins, T. / Garcia-Pardo, J. / Skenderovic, A. / Gebel, J. / Putyrski, M. / Vorobyov, A. / Busse, P. / Varga, G. / Kuzikov, M. / Zaliani, A. ...Maculins, T. / Garcia-Pardo, J. / Skenderovic, A. / Gebel, J. / Putyrski, M. / Vorobyov, A. / Busse, P. / Varga, G. / Kuzikov, M. / Zaliani, A. / Rahighi, S. / Schaeffer, V. / Parnham, M.J. / Sidhu, S.S. / Ernst, A. / Dotsch, V. / Akutsu, M. / Dikic, I. |
External links | Cell Chem Biol / PubMed:32726587 |
Methods | X-ray diffraction |
Resolution | 2.6 - 3.2 Å |
Structure data | PDB-6xx0: PDB-6yek: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | PROTEIN BINDING / Inhibitor / Ubiquitin / Cell signaling / NF-kB pathway |