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Title | A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity. |
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Journal, issue, pages | J Immunol., Vol. 205, Page 2287-2300, Year 2020 |
Publish date | Feb 5, 2020 (structure data deposition date) |
Authors | Pedersen, H. / Jensen, R.K. / Jensen, J.M.B. / Fox, R. / Pedersen, D.V. / Olesen, H.G. / Hansen, A.G. / Christiansen, D. / Mazarakis, S.M.M. / Lojek, N. ...Pedersen, H. / Jensen, R.K. / Jensen, J.M.B. / Fox, R. / Pedersen, D.V. / Olesen, H.G. / Hansen, A.G. / Christiansen, D. / Mazarakis, S.M.M. / Lojek, N. / Hansen, P. / Gadeberg, T.A.F. / Zarantonello, A. / Laursen, N.S. / Mollnes, T.E. / Johnson, M.B. / Stevens, B. / Thiel, S. / Andersen, G.R. |
External links | J Immunol. / PubMed:32938727 |
Methods | X-ray diffraction |
Resolution | 1.5 Å |
Structure data | PDB-6xzu: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / complex / complement / nanobody / innate immune system |