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-Structure paper
Title | Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation. |
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Journal, issue, pages | Elife, Vol. 9, Year 2020 |
Publish date | Aug 21, 2019 (structure data deposition date) |
Authors | Kazman, P. / Vielberg, M.T. / Pulido Cendales, M.D. / Hunziger, L. / Weber, B. / Hegenbart, U. / Zacharias, M. / Kohler, R. / Schonland, S. / Groll, M. / Buchner, J. |
External links | Elife / PubMed:32151314 |
Methods | X-ray diffraction |
Resolution | 1.55 - 2.5 Å |
Structure data | PDB-6sm1: PDB-6sm2: |
Chemicals | ChemComp-CA: ChemComp-PEG: ChemComp-PGE: ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / AL Amyloidosis / Antibody Folding / Protein Stability / Dynamics / PROTEIN FIBRIL |