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-Structure paper
Title | Novel Potent and Highly Selective Benzoimidazole-based Phosphodiesterase 10 Inhibitors with Improved Solubility and Pharmacokinetic Properties for the Treatment of Pulmonary Arterial Hypertension |
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Journal, issue, pages | To Be Published |
Publish date | Sep 24, 2019 (structure data deposition date) |
![]() | Yang, Y. / Zhang, S. / Zhou, Q. / Huang, Y.-Y. / Huang, J. / Li, Z. / Gao, Y. / Wu, Y. / Wu, D. / Luo, H.-B. / Guo, L. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.50003487525 Å |
Structure data | ![]() PDB-6kze: |
Chemicals | ![]() ChemComp-DZU: ![]() ChemComp-ZN: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / PDE10A inhibitor |