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-Structure paper
Title | Discovery and Optimization of Chromone Derivatives as Novel Selective Phosphodiesterase 10 Inhibitors. |
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Journal, issue, pages | Acs Chem Neurosci, Vol. 11, Page 1058-1071, Year 2020 |
Publish date | Aug 7, 2019 (structure data deposition date) |
Authors | Yu, Y.F. / Zhang, C. / Huang, Y.Y. / Zhang, S. / Zhou, Q. / Li, X. / Lai, Z. / Li, Z. / Gao, Y. / Wu, Y. ...Yu, Y.F. / Zhang, C. / Huang, Y.Y. / Zhang, S. / Zhou, Q. / Li, X. / Lai, Z. / Li, Z. / Gao, Y. / Wu, Y. / Guo, L. / Wu, D. / Luo, H.B. |
External links | Acs Chem Neurosci / PubMed:32105440 |
Methods | X-ray diffraction |
Resolution | 2.60002905998 - 2.7 Å |
Structure data | PDB-6ko0: PDB-6ko1: |
Chemicals | ChemComp-DKU: ChemComp-ZN: ChemComp-MG: ChemComp-HOH: ChemComp-DL0: |
Source |
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Keywords | HYDROLASE / PDE10A inhibitor |