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-Structure paper
Title | A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases. |
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Journal, issue, pages | Sci Rep, Vol. 9, Page 11436-11436, Year 2019 |
Publish date | Jun 26, 2019 (structure data deposition date) |
![]() | Nishimiya, D. / Kawaguchi, Y. / Kodama, S. / Nasu, H. / Yano, H. / Yamaguchi, A. / Tamura, M. / Hashimoto, R. |
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Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | ![]() PDB-6kbr: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / Protein engineering / Cystine knot protein / Protease inhibitor / Structural analysis / PROTEIN BINDING / HYDROLASE-HYDROLASE INHIBITOR complex |