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-Structure paper
Title | Structural Basis of AZD9291 Selectivity for EGFR T790M. |
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Journal, issue, pages | J. Med. Chem., Vol. 63, Page 8502-8511, Year 2020 |
Publish date | Apr 21, 2019 (structure data deposition date) |
![]() | Yan, X.E. / Ayaz, P. / Zhu, S.J. / Zhao, P. / Liang, L. / Zhang, C.H. / Wu, Y.C. / Li, J.L. / Choi, H.G. / Huang, X. ...Yan, X.E. / Ayaz, P. / Zhu, S.J. / Zhao, P. / Liang, L. / Zhang, C.H. / Wu, Y.C. / Li, J.L. / Choi, H.G. / Huang, X. / Shan, Y. / Shaw, D.E. / Yun, C.H. |
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Methods | X-ray diffraction |
Resolution | 2.307 - 2.551 Å |
Structure data | ![]() PDB-6jwl: ![]() PDB-6jx0: ![]() PDB-6jx4: ![]() PDB-6jxt: |
Chemicals | ![]() ChemComp-YY3: ![]() ChemComp-HOH: ![]() ChemComp-CL: |
Source |
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![]() | TRANSFERASE / Complex / Inhibitor / EGFR. / ONCOPROTEIN / EGFR |