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TitleOxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation.
Journal, issue, pagesNucleic Acids Res., Vol. 46, Page 10827-10839, Year 2018
Publish dateJul 26, 2016 (structure data deposition date)
AuthorsGruber, D.R. / Toner, J.J. / Miears, H.L. / Shernyukov, A.V. / Kiryutin, A.S. / Lomzov, A.A. / Endutkin, A.V. / Grin, I.R. / Petrova, D.V. / Kupryushkin, M.S. ...Gruber, D.R. / Toner, J.J. / Miears, H.L. / Shernyukov, A.V. / Kiryutin, A.S. / Lomzov, A.A. / Endutkin, A.V. / Grin, I.R. / Petrova, D.V. / Kupryushkin, M.S. / Yurkovskaya, A.V. / Johnson, E.C. / Okon, M. / Bagryanskaya, E.G. / Zharkov, D.O. / Smirnov, S.L.
External linksNucleic Acids Res. / PubMed:30289469
MethodsNMR (solution)
Structure data

PDB-5l06:
Solution Structure of a DNA Dodecamer with 5-methylcytosine at the 3rd Position
Method: SOLUTION NMR

PDB-5l2g:
Solution Structure of a DNA Dodecamer with 5-methylcytosine at the 9th Position
Method: SOLUTION NMR

PDB-5trn:
Solution Structure of a DNA Dodecamer with 8-oxoguanine at the 4th position and 5-methylcytosine at the 9th position
Method: SOLUTION NMR

PDB-5uz1:
Solution Structure of a DNA Dodecamer with 5-methylcytosine at the 3rd position and 8-oxoguanine at the 10th position
Method: SOLUTION NMR

PDB-5uz2:
Solution Structure of a DNA Dodecamer with 5-methylcytosine at the 3rd and 9th position and 8-oxoguanine at the 10th position
Method: SOLUTION NMR

PDB-5uz3:
Solution Structure of a DNA Dodecamer with 5-methylcytosine at the 9th position and 8-oxoguanine at the 10th position
Method: SOLUTION NMR

PDB-6als:
Solution structure of a DNA dodecamer with 5-methylcytosine at the 3rd and 9th position and 8-oxoguanine at the 4th position
Method: SOLUTION NMR

PDB-6alt:
Solution structure of a DNA dodecamer with 5-methylcytosine at the 3rd and 9th position
Method: SOLUTION NMR

PDB-6alu:
Solution structure of a DNA dodecamer with 5-methylcytosine at the 3rd and 8-oxoguanine at the 4th position
Method: SOLUTION NMR

Source
  • synthetic construct (others)
KeywordsDNA / Drew-Dickerson / non-canonical / modified DNA / methylated DNA / epigenetics / CpG site / 8-oxoguanine / oxidized DNA / 5-methylcytosine / DNA damage / DNA adduct / lesion

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