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-Structure paper
Title | Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 14, Page 1150-1158, Year 2018 |
Publish date | Sep 6, 2017 (structure data deposition date) |
Authors | Suno, R. / Lee, S. / Maeda, S. / Yasuda, S. / Yamashita, K. / Hirata, K. / Horita, S. / Tawaramoto, M.S. / Tsujimoto, H. / Murata, T. ...Suno, R. / Lee, S. / Maeda, S. / Yasuda, S. / Yamashita, K. / Hirata, K. / Horita, S. / Tawaramoto, M.S. / Tsujimoto, H. / Murata, T. / Kinoshita, M. / Yamamoto, M. / Kobilka, B.K. / Vaidehi, N. / Iwata, S. / Kobayashi, T. |
External links | Nat. Chem. Biol. / PubMed:30420692 |
Methods | X-ray diffraction |
Resolution | 2.3 - 3 Å |
Structure data | PDB-5yc8: PDB-5zk3: PDB-5zk8: PDB-5zkb: PDB-5zkc: |
Chemicals | ChemComp-3C0: ChemComp-HG: ChemComp-HOH: ChemComp-QNB: ChemComp-82F: |
Source |
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Keywords | MEMBRANE PROTEIN / GPCR crystallography / rationally thermostabilized mutant / MEMBRANE PROTEIN/INHIBITOR / MEMBRANE PROTEIN-INHIBITOR complex |