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Structure paper

TitleInsights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase.
Journal, issue, pagesBiochim Biophys Acta Bioenerg, Vol. 1860, Page 375-382, Year 2019
Publish dateFeb 23, 2018 (structure data deposition date)
AuthorsShiba, T. / Inaoka, D.K. / Takahashi, G. / Tsuge, C. / Kido, Y. / Young, L. / Ueda, S. / Balogun, E.O. / Nara, T. / Honma, T. ...Shiba, T. / Inaoka, D.K. / Takahashi, G. / Tsuge, C. / Kido, Y. / Young, L. / Ueda, S. / Balogun, E.O. / Nara, T. / Honma, T. / Tanaka, A. / Inoue, M. / Saimoto, H. / Harada, S. / Moore, A.L. / Kita, K.
External linksBiochim Biophys Acta Bioenerg / PubMed:30910528
MethodsX-ray diffraction
Resolution2.3 - 2.71 Å
Structure data

PDB-5zdp:
Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ferulenol
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

PDB-5zdq:
Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with COLLETOCHLORIN B
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5zdr:
Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative
Method: X-RAY DIFFRACTION / Resolution: 2.59 Å

Chemicals

ChemComp-FE:
Unknown entry

ChemComp-OH:
HYDROXIDE ION

ChemComp-OXY:
OXYGEN MOLECULE

ChemComp-9AU:
4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one

ChemComp-HOH:
WATER

ChemComp-RNB:
3-chloro-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4,6-dihydroxy-2-methylbenzaldehyde

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-CHW:
3-chloro-4,6-dihydroxy-5-[(2E,6E,8S)-8-hydroxy-3,7-dimethylnona-2,6-dien-1-yl]-2-methylbenzaldehyde

Source
  • trypanosoma brucei brucei (eukaryote)
KeywordsMEMBRANE PROTEIN / MEMBRANE BOUND DIIRON PROTEIN / OXIDOREDUCTASE

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