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Title | A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. |
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Journal, issue, pages | Sci Rep, Vol. 8, Page 3660-3660, Year 2018 |
Publish date | Oct 10, 2017 (structure data deposition date) |
Authors | Kannt, A. / Rajagopal, S. / Kadnur, S.V. / Suresh, J. / Bhamidipati, R.K. / Swaminathan, S. / Hallur, M.S. / Kristam, R. / Elvert, R. / Czech, J. ...Kannt, A. / Rajagopal, S. / Kadnur, S.V. / Suresh, J. / Bhamidipati, R.K. / Swaminathan, S. / Hallur, M.S. / Kristam, R. / Elvert, R. / Czech, J. / Pfenninger, A. / Rudolph, C. / Schreuder, H. / Chandrasekar, D.V. / Mane, V.S. / Birudukota, S. / Shaik, S. / Zope, B.R. / Burri, R.R. / Anand, N.N. / Thakur, M.K. / Singh, M. / Parveen, R. / Kandan, S. / Mullangi, R. / Yura, T. / Gosu, R. / Ruf, S. / Dhakshinamoorthy, S. |
External links | Sci Rep / PubMed:29483571 |
Methods | X-ray diffraction |
Resolution | 1.99 - 2.49 Å |
Structure data | PDB-5yjf: PDB-5yji: |
Chemicals | ChemComp-SAH: ChemComp-8WO: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / NNMT / MNA / T2D |