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-Structure paper
Title | Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 27, Page 2678-2682, Year 2017 |
Publish date | Mar 10, 2017 (structure data deposition date) |
![]() | Cheruvallath, Z.S. / Gwaltney, S.L. / Sabat, M. / Tang, M. / Wang, H. / Jennings, A. / Hosfield, D. / Lee, B. / Wu, Y. / Halkowycz, P. / Grimshaw, C.E. |
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Methods | X-ray diffraction |
Resolution | 2.08 - 2.39 Å |
Structure data | ![]() PDB-5v4w: ![]() PDB-5v4x: |
Chemicals | ![]() ChemComp-GLC: ![]() ChemComp-8WM: ![]() ChemComp-IOD: ![]() ChemComp-HOH: ![]() ChemComp-8WJ: |
Source |
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![]() | transferase/transferase activator / activator / complex / allosteric / transferase-transferase activator complex / glucokinase |