+Search query
-Structure paper
Title | Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations. |
---|---|
Journal, issue, pages | Sci Rep, Vol. 7, Page 7501-7501, Year 2017 |
Publish date | Aug 31, 2010 (structure data deposition date) |
Authors | Counago, R.M. / Allerston, C.K. / Savitsky, P. / Azevedo, H. / Godoi, P.H. / Wells, C.I. / Mascarello, A. / de Souza Gama, F.H. / Massirer, K.B. / Zuercher, W.J. ...Counago, R.M. / Allerston, C.K. / Savitsky, P. / Azevedo, H. / Godoi, P.H. / Wells, C.I. / Mascarello, A. / de Souza Gama, F.H. / Massirer, K.B. / Zuercher, W.J. / Guimaraes, C.R.W. / Gileadi, O. |
External links | Sci Rep / PubMed:28790404 |
Methods | X-ray diffraction |
Resolution | 2 - 2.4 Å |
Structure data | PDB-3op5: PDB-5ukf: PDB-5uu1: PDB-5uvf: |
Chemicals | ChemComp-REB: ChemComp-EDO: ChemComp-GOL: ChemComp-HOH: ChemComp-8E1: ChemComp-PO4: ChemComp-CL: ChemComp-PEG: ChemComp-7DZ: |
Source |
|
Keywords | TRANSFERASE / Adenosine Triphosphate / Amino Acid Sequence / Binding Sites / Catalytic Domain / Models / Molecular / Molecular Sequence Data / Phosphotransferases / Protein Conformation / Protein Folding / Surface Entropy Reduction / Structural Genomics / Structural Genomics Consortium / SGC / Transferase/Transferase Inhibitor / protein kinase domain / Transferase-Transferase Inhibitor Complex |