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-Structure paper
Title | Carboxamide Spleen Tyrosine Kinase (Syk) Inhibitors: Leveraging Ground State Interactions To Accelerate Optimization. |
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Journal, issue, pages | ACS Med Chem Lett, Vol. 7, Page 1151-1155, Year 2016 |
Publish date | Oct 3, 2016 (structure data deposition date) |
Authors | Ellis, J.M. / Altman, M.D. / Cash, B. / Haidle, A.M. / Kubiak, R.L. / Maddess, M.L. / Yan, Y. / Northrup, A.B. |
External links | ACS Med Chem Lett / PubMed:27994755 |
Methods | X-ray diffraction |
Resolution | 1.49 Å |
Structure data | PDB-5tiu: |
Chemicals | ChemComp-7CU: ChemComp-HOH: |
Source |
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Keywords | Transferase/Transferase Inhibitor / Carboxamide Spleen Tyrosine Kinase (Syk) / Transferase-Transferase Inhibitor complex |