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-Structure paper
Title | Structural basis for regiospecific midazolam oxidation by human cytochrome P450 3A4. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. U.S.A., Vol. 114, Page 486-491, Year 2017 |
Publish date | Sep 20, 2016 (structure data deposition date) |
Authors | Sevrioukova, I.F. / Poulos, T.L. |
External links | Proc. Natl. Acad. Sci. U.S.A. / PubMed:28031486 |
Methods | X-ray diffraction |
Resolution | 2.7 Å |
Structure data | PDB-5te8: |
Chemicals | ChemComp-HEM: ChemComp-08J: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / cytochrome P450 / CYP3A4 / monooxygenase / drug metabolism / midazolam |