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-Structure paper
Title | A fragment-based approach to developing inhibitors of the cryptic pocket of the Polo-Like Kinase 1 Polo-Box Domain. |
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Journal, issue, pages | To Be Published |
Publish date | Mar 10, 2017 (structure data deposition date) |
![]() | Kunciw, D.L. / De Fusco, C. / Rossmann, M. / Stokes, J.E. / Renzetti, A. / Sore, H.F. / Hyvonen, M. / Spring, D.R. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.81 - 2.68 Å |
Structure data | ![]() PDB-5nei: ![]() PDB-5nn2: |
Chemicals | ![]() ChemComp-8VB: ![]() ChemComp-HOH: ![]() ChemComp-Z24: |
Source |
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![]() | TRANSFERASE / PLK1 / PBD1 / mitosis / small molecule |