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Title | Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1. |
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Journal, issue, pages | Sci Rep, Vol. 7, Page 39392-39392, Year 2017 |
Publish date | Aug 19, 2016 (structure data deposition date) |
Authors | Hinchliffe, P. / Yang, Q.E. / Portal, E. / Young, T. / Li, H. / Tooke, C.L. / Carvalho, M.J. / Paterson, N.G. / Brem, J. / Niumsup, P.R. ...Hinchliffe, P. / Yang, Q.E. / Portal, E. / Young, T. / Li, H. / Tooke, C.L. / Carvalho, M.J. / Paterson, N.G. / Brem, J. / Niumsup, P.R. / Tansawai, U. / Lei, L. / Li, M. / Shen, Z. / Wang, Y. / Schofield, C.J. / Mulholland, A.J. / Shen, J. / Fey, N. / Walsh, T.R. / Spencer, J. |
External links | Sci Rep / PubMed:28059088 |
Methods | X-ray diffraction |
Resolution | 1.55 - 1.75 Å |
Structure data | PDB-5lrm: PDB-5lrn: |
Chemicals | ChemComp-ZN: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / phosphoethanolamine / colistin / metalloenzyme / zinc / phosphotehanolamine / antibiotic resistance |