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-Structure paper
Title | Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl)methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1. |
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Journal, issue, pages | Eur. J. Med. Chem., Vol. 122, Page 185-195, Year 2016 |
Publish date | May 17, 2016 (structure data deposition date) |
Authors | Simon, P. / Baszczynski, O. / Saman, D. / Stepan, G. / Hu, E. / Lansdon, E.B. / Jansa, P. / Janeba, Z. |
External links | Eur. J. Med. Chem. / PubMed:27371922 |
Methods | X-ray diffraction |
Resolution | 2.402 Å |
Structure data | PDB-5k14: |
Chemicals | ChemComp-IB1: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / HIV-1 / reverse transcriptase / NNRTI / inhibitor complex / TRANSFERASE-TRANSFERASE INHIBITOR complex |