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-Structure paper
Title | Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity. |
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Journal, issue, pages | J. Thromb. Haemost., Vol. 14, Page 1629-1638, Year 2016 |
Publish date | Jan 28, 2016 (structure data deposition date) |
Authors | Zhou, X. / Weeks, S.D. / Ameloot, P. / Callewaert, N. / Strelkov, S.V. / Declerck, P.J. |
External links | J. Thromb. Haemost. / PubMed:27279497 |
Methods | X-ray diffraction |
Resolution | 2.85 - 3.05 Å |
Structure data | PDB-5hvf: PDB-5hvg: PDB-5hvh: |
Chemicals | ChemComp-NAG: ChemComp-ZN: ChemComp-FLC: ChemComp-HOH: ChemComp-ACT: |
Source |
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Keywords | hydrolase/hydrolase inhibitor / procarboxypeptidase U / thrombin-activatable fibrinolysis inhibitor / TAFI / procarboxypeptidase R / plasma procarboxypeptidase B / nanobody / antibody fragment / protein complex / HYDROLASE / hydrolase-hydrolase inhibitor complex |