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TitleSystem-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Journal, issue, pagesMol. Cell, Vol. 62, Page 121-136, Year 2016
Publish dateJun 24, 2015 (structure data deposition date)
AuthorsZhang, W. / Wu, K.P. / Sartori, M.A. / Kamadurai, H.B. / Ordureau, A. / Jiang, C. / Mercredi, P.Y. / Murchie, R. / Hu, J. / Persaud, A. ...Zhang, W. / Wu, K.P. / Sartori, M.A. / Kamadurai, H.B. / Ordureau, A. / Jiang, C. / Mercredi, P.Y. / Murchie, R. / Hu, J. / Persaud, A. / Mukherjee, M. / Li, N. / Doye, A. / Walker, J.R. / Sheng, Y. / Hao, Z. / Li, Y. / Brown, K.R. / Lemichez, E. / Chen, J. / Tong, Y. / Harper, J.W. / Moffat, J. / Rotin, D. / Schulman, B.A. / Sidhu, S.S.
External linksMol. Cell / PubMed:26949039
MethodsX-ray diffraction
Resolution2.05 - 3.03 Å
Structure data

PDB-5c7j:
CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-5c7m:
CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT
Method: X-RAY DIFFRACTION / Resolution: 3.03 Å

PDB-5hpk:
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: NEDD4L and UbV NL.1
Method: X-RAY DIFFRACTION / Resolution: 2.431 Å

PDB-5hpl:
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: Rsp5 and UbV R5.4
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

PDB-5hps:
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-5hpt:
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1, Ubv P2.3 and UBCH7
Method: X-RAY DIFFRACTION / Resolution: 2.84 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsLIGASE/SIGNALING PROTEIN / LIGASE / UBIQUITIN-PROTEIN LIGASE / UBIQUITIN VARIANT / Structural Genomics Consortium / SGC / Structural Genomics / LIGASE-SIGNALING PROTEIN complex / HECT / E3 ligase / NEDD4L / ubiquitin / Ubv / HECT E3 / Rsp5 / LIGASE/TRANSFERASE / WWP1 / UBCH7 / LIGASE-TRANSFERASE complex

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