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TitleThe C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.
Journal, issue, pagesPLoS Pathog., Vol. 12, Page e1005886-e1005886, Year 2016
Publish dateDec 15, 2015 (structure data deposition date)
AuthorsTay, M.Y. / Smith, K. / Ng, I.H. / Chan, K.W. / Zhao, Y. / Ooi, E.E. / Lescar, J. / Luo, D. / Jans, D.A. / Forwood, J.K. / Vasudevan, S.G.
External linksPLoS Pathog. / PubMed:27622521
MethodsX-ray diffraction
Resolution2.1 - 2.2 Å
Structure data

PDB-5fc8:
Mouse importin alpha: Dengue 3 NS5 C-terminal NLS peptide complex
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5hhg:
Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • dengue virus 3
  • mus musculus (house mouse)
  • dengue virus type 2 (strain puerto rico/pr159-s1/1969)
KeywordsPROTEIN TRANSPORT/Viral Protein / Dengue / NS5 / Importin / PROTEIN TRANSPORT-Viral Protein complex

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