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-Structure paper
Title | Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis. |
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Journal, issue, pages | Sci Rep, Vol. 5, Page 16950-16950, Year 2015 |
Publish date | Sep 11, 2015 (structure data deposition date) |
Authors | de Cima, S. / Polo, L.M. / Diez-Fernandez, C. / Martinez, A.I. / Cervera, J. / Fita, I. / Rubio, V. |
External links | Sci Rep / PubMed:26592762 |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.6 Å |
Structure data | PDB-5dot: PDB-5dou: |
Chemicals | ChemComp-NI: ChemComp-EDO: ChemComp-GOL: ChemComp-HOH: ChemComp-MG: ChemComp-K: ChemComp-PO4: ChemComp-ADP: ChemComp-NLG: ChemComp-CL: |
Source |
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Keywords | LIGASE / Carbamoyl Phosphate Synthase (ammonia utilizing) / Carbamoyl Phosphate / Ammonia / N-acetyl-L-glutamate / Adenosine Triphosphate / apo / urea cycle / Multi-domain / Allosteric site / Rare disease / CPS1 deficiency / Hyperammonemia / ligand-bound |