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-Structure paper
Title | Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma. |
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Journal, issue, pages | Protein Eng. Des. Sel., Vol. 29, Page 135-147, Year 2016 |
Publish date | Aug 17, 2015 (structure data deposition date) |
![]() | Grossman, I. / Ilani, T. / Fleishman, S.J. / Fass, D. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.05 - 2.3 Å |
Structure data | ![]() PDB-5d8i: ![]() PDB-5d93: ![]() PDB-5d96: |
Chemicals | ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / enzyme / disulfide bonds / thioredoxin fold / inhibitor / antibody / IMMUNE SYSTEM / dual-specificity |