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-Structure paper
Title | Molecular basis of in vitro affinity maturation and functional evolution of a neutralizing anti-human GM-CSF antibody. |
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Journal, issue, pages | Mabs, Vol. 8, Page 176-186, Year 2016 |
Publish date | Jun 25, 2015 (structure data deposition date) |
Authors | Eylenstein, R. / Weinfurtner, D. / Hartle, S. / Strohner, R. / Bottcher, J. / Augustin, M. / Ostendorp, R. / Steidl, S. |
External links | Mabs / PubMed:26406987 |
Methods | X-ray diffraction |
Resolution | 1.88 - 2.95 Å |
Structure data | PDB-5c7x: PDB-5d70: PDB-5d71: PDB-5d72: PDB-5d7s: |
Chemicals | ChemComp-PGE: ChemComp-PEG: ChemComp-PG6: ChemComp-HOH: ChemComp-SO4: ChemComp-BUD: |
Source |
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Keywords | IMMUNE SYSTEM / GM-CSF / affinity maturation / phage display / cytokine / antibody / PROTEROS BIOSTRUCTURES GMBH |