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-Structure paper
Title | Spiroepoxytriazoles Are Fumagillin-like Irreversible Inhibitors of MetAP2 with Potent Cellular Activity. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 11, Page 1001-1011, Year 2016 |
Publish date | Jul 16, 2015 (structure data deposition date) |
![]() | Morgen, M. / Jost, C. / Malz, M. / Janowski, R. / Niessing, D. / Klein, C.D. / Gunkel, N. / Miller, A.K. |
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Methods | X-ray diffraction |
Resolution | 1.49 - 1.75 Å |
Structure data | ![]() PDB-5cls: ![]() PDB-5d6e: ![]() PDB-5d6f: |
Chemicals | ![]() ChemComp-CO: ![]() ChemComp-DMS: ![]() ChemComp-GOL: ![]() ChemComp-52T: ![]() ChemComp-CIT: ![]() ChemComp-CL: ![]() ChemComp-HOH: ![]() ChemComp-94A: ![]() ChemComp-TBU: ![]() ChemComp-57R: ![]() ChemComp-EDO: |
Source |
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![]() | HYDROLASE / MetAP2 / methionine aminopeptidase-2 / inhibitor / spiroepoxytriazole / Methionine aminopeptidase 2 / Spiroepoxytriazoles |