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Structure paper

TitleSuppression of conformational heterogeneity at a protein-protein interface.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 9028-9033, Year 2015
Publish dateNov 11, 2014 (structure data deposition date)
AuthorsDeis, L.N. / Wu, Q. / Wang, Y. / Qi, Y. / Daniels, K.G. / Zhou, P. / Oas, T.G.
External linksProc. Natl. Acad. Sci. USA / PubMed:26157136
MethodsX-ray diffraction
Resolution1.87 - 2.307 Å
Structure data

PDB-4wwi:
Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution
Method: X-RAY DIFFRACTION / Resolution: 2.307 Å

PDB-4zmd:
C domain of staphylococcal protein A mutant - Q9W
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-4znc:
Fc fragment of human IgG in complex with the C domain of staphylococcal protein A mutant - Q9W
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus (bacteria)
  • homo sapiens (human)
KeywordsPROTEIN BINDING / three-helix bundle / conformational heterogeneity / S. aureus / antibody binding / Staphylococcal protein A / SpA / three-helix-bundle / antibody / IgG / protein-binding domain

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