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-Structure paper
Title | Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 23, Page 4462-4471, Year 2015 |
Publish date | Apr 10, 2015 (structure data deposition date) |
![]() | Fonseca, E.M. / Trivella, D.B. / Scorsato, V. / Dias, M.P. / Bazzo, N.L. / Mandapati, K.R. / de Oliveira, F.L. / Ferreira-Halder, C.V. / Pilli, R.A. / Miranda, P.C. / Aparicio, R. |
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Methods | X-ray diffraction |
Resolution | 2.1 - 2.41 Å |
Structure data | ![]() PDB-4z99: ![]() PDB-4z9a: ![]() PDB-4z9b: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-PMS: ![]() ChemComp-B85: |
Source |
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![]() | HYDROLASE / LMW-PTPase / LMW-PTP / Low molecular weight cytosolic acid phosphatase / Red cell acid phosphatase 1 / Adipocyte acid phosphatase / Protein Tyrosine Phosphatase / protein-ligand complex / phenylmethanesulfonic acid / benzylphosphonic acid |