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-Structure paper
Title | Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. |
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Journal, issue, pages | Cell, Vol. 161, Page 1633-1643, Year 2015 |
Publish date | Mar 30, 2015 (structure data deposition date) |
Authors | Chrencik, J.E. / Roth, C.B. / Terakado, M. / Kurata, H. / Omi, R. / Kihara, Y. / Warshaviak, D. / Nakade, S. / Asmar-Rovira, G. / Mileni, M. ...Chrencik, J.E. / Roth, C.B. / Terakado, M. / Kurata, H. / Omi, R. / Kihara, Y. / Warshaviak, D. / Nakade, S. / Asmar-Rovira, G. / Mileni, M. / Mizuno, H. / Griffith, M.T. / Rodgers, C. / Han, G.W. / Velasquez, J. / Chun, J. / Stevens, R.C. / Hanson, M.A. |
External links | Cell / PubMed:26091040 |
Methods | X-ray diffraction |
Resolution | 2.9 - 3 Å |
Structure data | PDB-4z34: PDB-4z35: PDB-4z36: |
Chemicals | ChemComp-ON7: ChemComp-1WV: ChemComp-ON9: ChemComp-HOH: ChemComp-ON3: |
Source |
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Keywords | TRANSPORT PROTEIN/inhibitor / human lysophosphatidic acid receptor 1 (LPA1) / G-protein coupled receptor (GPCR) / membrane protein / antagonist / endogenous ligand / PSI-biology / structural genomics / GPCR network / lipidic cubic phase (LCP) / Compound design / polypharmacology / lipid receptor / TRANSPORT PROTEIN-inhibitor complex / novel disulfide bond engineering |