+Search query
-Structure paper
Title | Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS. |
---|---|
Journal, issue, pages | J. Biol. Chem., Vol. 290, Page 19403-19422, Year 2015 |
Publish date | Nov 10, 2014 (structure data deposition date) |
Authors | Tomar, S. / Johnston, M.L. / St John, S.E. / Osswald, H.L. / Nyalapatla, P.R. / Paul, L.N. / Ghosh, A.K. / Denison, M.R. / Mesecar, A.D. |
External links | J. Biol. Chem. / PubMed:26055715 |
Methods | X-ray diffraction |
Resolution | 1.62 - 2.1 Å |
Structure data | PDB-4rsp: PDB-4ylu: |
Chemicals | ChemComp-HOH: ChemComp-R30: ChemComp-ACT: |
Source |
|
Keywords | Hydrolase/hydrolase Inhibitor / protease / Hydrolase-hydrolase Inhibitor complex |