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-Structure paper
Title | 10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A. |
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Journal, issue, pages | J. Med. Chem., Vol. 58, Page 3131-3143, Year 2015 |
Publish date | Mar 5, 2015 (structure data deposition date) |
Authors | Falke, H. / Chaikuad, A. / Becker, A. / Loaec, N. / Lozach, O. / Abu Jhaisha, S. / Becker, W. / Jones, P.G. / Preu, L. / Baumann, K. ...Falke, H. / Chaikuad, A. / Becker, A. / Loaec, N. / Lozach, O. / Abu Jhaisha, S. / Becker, W. / Jones, P.G. / Preu, L. / Baumann, K. / Knapp, S. / Meijer, L. / Kunick, C. |
External links | J. Med. Chem. / PubMed:25730262 |
Methods | X-ray diffraction |
Resolution | 1.4 - 2.58 Å |
Structure data | PDB-4ylj: PDB-4ylk: PDB-4yll: |
Chemicals | ChemComp-PG4: ChemComp-SO4: ChemComp-4E1: ChemComp-HOH: ChemComp-EDO: ChemComp-4E2: ChemComp-IOD: ChemComp-4E3: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / halogen / inhibitor / Structural Genomics / Structural Genomics Consortium / SGC / TRANSFERASE-TRANSFERASE INHIBITOR complex |