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Title | Inhibiting the beta-Lactamase of Mycobacterium tuberculosis (Mtb) with Novel Boronic Acid Transition-State Inhibitors (BATSIs). |
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Journal, issue, pages | ACS Infect Dis, Vol. 1, Page 234-242, Year 2015 |
Publish date | Dec 9, 2014 (structure data deposition date) |
Authors | Kurz, S.G. / Hazra, S. / Bethel, C.R. / Romagnoli, C. / Caselli, E. / Prati, F. / Blanchard, J.S. / Bonomo, R.A. |
External links | ACS Infect Dis / PubMed:27622739 |
Methods | X-ray diffraction |
Resolution | 1.4 Å |
Structure data | PDB-4x6t: |
Chemicals | ChemComp-PO4: ChemComp-3Y6: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / beta-lactamase / transition state inhibitor / structure based drug development / beta-lactams / boronates / penicillin binding protein. / HYDROLASE-HYDROLASE INHIBITOR complex |